VRTX P/E ratio: current value, 10-year range and year-by-year history
Cash & Leverage
VRTX's p/e ratio is higher than 65% of the last 10 years.
P/E ratio History
VRTX P/E ratio by year
Yearly range of VRTX’s p/e ratio from 2016 to 2026. Over the full period it ranged from -259.7 to 199.4, averaging 17.2.
| Year | Low | Average | High | Year-end |
|---|---|---|---|---|
| 2026 | 25.1 | 28.7 | 32.6 | 30.0 |
| 2025 | -233.5 | -63.6 | 34.3 | 29.6 |
| 2024 | -259.7 | -104.8 | 32.1 | -183.0 |
| 2023 | 22.1 | 26.2 | 30.8 | 30.5 |
| 2022 | 22.1 | 25.4 | 30.8 | 22.8 |
| 2021 | 17.9 | 22.6 | 26.8 | 24.3 |
| 2020 | 20.2 | 38.5 | 54.9 | 22.9 |
| 2019 | 19.5 | 22.4 | 48.5 | 48.5 |
| 2018 | 20.5 | 129.5 | 197.6 | 20.5 |
| 2017 | -229.8 | 83.5 | 199.4 | 192.1 |
| 2016 | -104.8 | -87.9 | -75.2 | -81.0 |
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How much the market pays for each dollar of annual profit. P/E = Stock Price / EPS. The raw number means little — what matters is whether it's high or low relative to the company's own history.
Price / Earnings Per ShareThe chart shows five color-coded historical zones: green (below 10th percentile) means historically very cheap, fading through lime and gray (the normal 25th–75th range) to orange and red (historically expensive). When the line sits in a green or lime zone, the stock is trading at an unusually low P/E relative to its own history.
- Cyclical businesses look cheapest on P/E at peak earnings — the "earnings trap." Use EV/EBITDA or normalised earnings for energy, materials, and financials.
- A falling P/E trend may signal a business in structural decline, not a buying opportunity.
Is VRTX P/E ratio High or Low Right Now?
Vertex Pharmaceuticals Incorporated's P/E ratio is currently 30.0, which is above average relative to its 10-year historical range. The 10-year median P/E ratio for VRTX is approximately 26.4. See all VRTX valuation metrics →
Unlock 10y, 15y, 20y, and 30y history with peer comparison and CSV export.