Alnylam Pharmaceuticals, Inc.ALNY

Where ALNY's P/E ratio sits inside its own 10-year distribution, with the yearly high, low and average.

$247.51-10.49 (-4.07%)Previous close
NASDAQHealthcare

ALNY P/E ratio: current value, 10-year range and year-by-year history

41.8Near historic high

ALNY's p/e ratio is higher than 95% of the last 10 years.

P/E ratio History

Historically priceyAbove avgAround avgBelow avgHistorically cheap
ALNY P/E ratio historyALNY P/E ratio from Sep 2023 to Sep 2026: low -478.35, high 2,046.75, latest 41.81.-680.3651.92784.21,516.482,248.76Sep 23Apr 24Nov 24Jul 25Feb 26Sep 26med -54.16

ALNY P/E ratio by year

Yearly range of ALNY’s p/e ratio from 2016 to 2026. Over the full period it ranged from -478.4 to 2,046.8, averaging 13.5.

ALNY P/E ratio — yearly low, average, high and year-end values
YearLowAverageHighYear-end
202634.790.8186.941.8
2025-195.2371.12,046.8176.0
2024-478.4-160.4-41.2-108.4
2023-47.5-27.2-19.7-46.2
2022-28.6-21.3-16.1-24.3
2021-29.4-22.6-17.0-23.6
2020-21.9-16.7-11.4-17.4
2019-16.0-10.8-8.4-14.1
2018-27.5-17.4-9.0-9.6
2017-26.7-15.9-7.7-24.2
2016-18.4-10.8-6.9-8.2

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How much the market pays for each dollar of annual profit. P/E = Stock Price / EPS. The raw number means little — what matters is whether it's high or low relative to the company's own history.

FormulaPrice / Earnings Per Share
Full guide
How to read this chart

The chart shows five color-coded historical zones: green (below 10th percentile) means historically very cheap, fading through lime and gray (the normal 25th–75th range) to orange and red (historically expensive). When the line sits in a green or lime zone, the stock is trading at an unusually low P/E relative to its own history.

Key caveats
  • Cyclical businesses look cheapest on P/E at peak earnings — the "earnings trap." Use EV/EBITDA or normalised earnings for energy, materials, and financials.
  • A falling P/E trend may signal a business in structural decline, not a buying opportunity.

Is ALNY P/E ratio High or Low Right Now?

Alnylam Pharmaceuticals, Inc.'s P/E ratio is currently 41.8, which is near historic high relative to its 10-year historical range. The 10-year median P/E ratio for ALNY is approximately -19.2. See all ALNY valuation metrics →

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